Scientific Research and Clinical Studies on the Effectiveness of the Mineral Silver Are Numerous

July 17, 2018; by Briana McDonald, (Silver Bulletin e-News Magazine Reprint) Whenever I tell people who have never heard about the mineral silver all of the many wonderful things it helps with I always get this same look of disbelief and so common the question, “Then why haven’t I heard of it by now if it’s so great?” Then the proceeding statement, “Show me the research.” For the skeptics who demand more, the scientific research and clinical studies on the effectiveness of the mineral silver are numerous. Here is some Colloidal Silver research and clinical studies supporting what anecdotal experience has already proven about the mineral silver.

  1. Anti-tumor activity of colloidal silver on MCF-7 human breast cancer cells:  

A 2009 Study to determine if colloidal silver had cytotoxic effects on MCF-7 breast cancer cells and its mechanism of cell death showed impressive results. MCF-7 breast cancer cells were treated with colloidal silver (ranged from 1.75 to 17.5 ng/mL) for 5 h at 37°C and 5% CO2 atmosphere. Cell Viability was evaluated by trypan blue exclusion method and the mechanism of cell death through detection of mono-oligonucleosomes using an ELISA kit and TUNEL assay. The production of NO, LDH, and Gpx, SOD, CAT, and Total antioxidant activities were evaluated by colorimetric assays.

The results showed that Colloidal silver had dose-dependent cytotoxic effect in MCF-7 breast cancer cells through induction of apoptosis, shown an LD50 (3.5 ng/mL) and LD100 (14 ng/mL) (*P<0.05), significantly decreased LDH (*P<0.05) and significantly increased SOD (*P<0.05) activities. However, the NO production, and Gpx, CAT, and Total antioxidant activities were not affected in MCF-7 breast cancer cells. PBMC were not altered by colloidal silver.

The researchers concluded that colloidal silver might be a potential alternative agent for human breast cancer therapy. ” (1)


  1. Colloidal Silver Controls Antibiotic- Resistant Superbugs: 

While employed at UCLA Medical School in the 80’s, Larry C. Ford, MD. documented over 650 different disease causing pathogens that were destroyed in minutes when exposed to small amounts of silver. (2) Colloidal Silver does not create resistance or immunity in the organisms that are killed by it which can not be overemphasized. The Centers or Disease Control and Prevention recently reported that more than 2 million people in the United States suffer illnesses every year as a result of antibiotic resistant infections and over 20 thousand die from these infections. (3)

  1. Colloidal Silver is a potent Anti-Viral: 

Colloidal Silver is not only an antibacterial but also an antiviral and can help people in the treatment of HIV/AIDS, pneumonia, herpes, shingles, and warts. Dr. Martin Hum from the Institute for Optimum Nutrition lists Colloidal Silver as one of the natural remedies to stop viruses fast. Colloidal Silver suffocates the virus and reduces the activity of the HIV virus in AIDS patients. There are also numerous accounts of silver helping those treat the hepatitis C virus. (4)

  1. Colloidal Silver Keeps Inflammation Levels Down: 

Researchers at the National Institute of Health studies the effects of inflammation after a treatment of colloidal silver and found that the inflamed skin of pigs treated with silver experienced near normal skin after seventy two hours while other treatment groups not treated with silver remained inflamed. (5)

  1. Colloidal Silver Has Been Shown to Help With Sinus Infections:

According to a study published in the International Forum for Allergy and Rhino-logy last year, Colloidal Silver also benefits people as a nasal spray. The aim of the study was to determine whether colloidal silver had any direct bactericidal effects on Staphylococcus aureus biofilms in vitro. S. aureus biofilms were grown from the ATCC 25923 reference strain on Minimum Biofilm Eradication Concentration (MBEC) device pegs, and treated with colloidal silver. Concentrations tested ranged from 10 to 150 μL colloidal silver diluted to 200 μL with sterile water in 50 μL cerebrospinal fluid (CSF) broth. Control pegs were exposed to equivalent volumes of CSF broth and sterile water. The sample size was 4 biomass values per treatment or control group. Confocal scanning laser microscopy and COMSTAT software were used to quantify biofilms 24 hours after treatment.  The results showed significant differences from control were found for all concentrations. The reduction in biomass was 98.9% and a maximum biomass reduction of 99.8% was reached with use of Colloidal Silver. The study concluded that “Colloidal Silver directly attenuates in vitro S. aures biofilms. (6)

  1. Colloidal Silver Prevents and Treats the Flu and the Common Cold: 

A 2011 study from the National Institute of Health took 100 children under the age of 12 experiencing symptoms from the common cold and nasal congestion and assigned them into two separate groups. The first was treated with a solution of colloidal silver and beta glucan and the second was treated with a saline solution. Even though both groups benefited from the treatment, 90% of the people in the Colloidal Silver group completely recovered. (7)

There is much more colloidal silver research and clinical studies than I could squeeze into one easy to read article. For more information please look into some of the below references.

Colloidal Silver Research & Clinical Studies

  1. Gibbins, Bruce Ph.D., AcryMed, Inc., Portland, OR April 2000
    Pre-clinical and Clinical Evaluation of a New Silver Anti-Microbial Chronic Wound Dressing “
  2. Nametka, Mary, RN, MSN, CS CWS, WCN, Associates in Wound Care, Kenosha, WI Oct. 2000
    A Hydrophilic Silver Antimicrobial Wound Dressing for Site Preparation and Maintenance of Human Skin Equivalent Grafts to Venus Leg Ulcers: Technical and Clinical Considerations
  3. Nametka, Mary, RN, MSN, CS CWS, WCN , Associates in Wound Care, Kenosha, WI May 2001
  4. Antimicrobial Silver Polymer Contact Layer for Treatment of Venous Leg Ulcers
  5. Nametka, Mary, RN, MSN, CS CWS, WCN , Associates in Wound Care, Kenosha, WI June 2001
    Clinical Protocol for use of Absorbent Silver Antimicrobial Polymer Dressings
  6. Nametka, Mary, RN, MSN, CS CWS, WCN , Associates in Wound Care, Kenosha, WI April 2002
    Silver Antimicrobial Hydrophilic Dressing Benefits Management of Recurrent Non-healing Wounds
  7. Nametka, Mary, RN, MSN, CS CWS, WCN , Associates in Wound Care, Kenosha, WI Sept. 2002
    Silver Antimicrobial Absorbent Wound Dressing Can Contribute to Cost Control in Home Care
  8. Smith, Latisha M.D ., Ostomy Wound Management, Feb. 2003
    Clinical Experience using Silver Antimicrobial Dressings on Venous Stasis Ulcers
  9. Gibbins, Bruce Ph.D., Ostomy Wound Management, Feb. 2003
    The Antimicrobial Benefits of Silver and the relevance of Microlattice Technology
  10. Rose, Susan RN, BSN, CWOCN , Gentiva Health Services, Tuscon, AZ. April 2003
    Importance of Assessment and Wound Bed Preparation in the Treatment of Chronic Wounds
  11. Paz-Altschul, Oscar M.D., FACS , Desert Regional Medical Center, Palm Springs, CA April 2003
    Silver Microlattice Uses in Chronic Wound Care
  12. Tamulonis, Ruth RN, MS, CWOCN , Marshalltown Medical & Surgical Center, Marshalltown, IA April 2003 The Use of a Unique Delivery Method of Ionic Silver: A Case Series
  13. Brandy, J. Christopher, MD, FACS, Caromont Wound Center Gastonia, NC April 2003
    Understanding the Role of Ionic Silver in Wound Bed Preparation
  14. Tamulonis, Ruth RN, MS, CWOCN , Marshalltown Medical & Surgical Center, Marshalltown, IA June 2003 A Paradigm Shift in Wound Management
  15. Trowsdale, Helen RN, BSN and Olveda, Mary RN, BSN A-Plus Family Care, SanAntonio, TX
    Meeting the Challenges for Wounds in Home Care with a Silver Amorphous Hydrogel and Collagen
  16. Agbim, Salome ND CNS APRN BC and Miner, Kimberly ND CNS CWCN Wound Care Associates, Englewood, CO Bioburden Control through the use of Silve Anti-moicrobial Gel on Contaminated Stage IV Pressure Ulcer
  17. McCord, Shannon MS, RN, CPNP, CNS, CCRN, WOCN, and Bookout, Kimberly BSN, RN, CWOCN, and McLane, Kathleen MSN,RN, CPNP, CWCN, COCN, and Helmrath, Michael MD Texas Children’s Hospital, Houston, TX June 2004 “Use of Silver Dressing with Neonatal Abdominal Evisceration”
  18. Marjorie Groom, RN, CWOCN, MSHCA, DAPWCA, Memorial Hosptial Belleville, IL April 2005 “Enhancing Venous Leg Ulcer Health with an Ionic Silver Hydrogel”
  19. Barbara Conway Salerno, RN, BSN, CWOCN, Eddy Visiting Nurses, Troy, NY April 2005 “The Use of Controlled-Release Ionic Silver Hydrogel in the Management of Chronic Wounds”
  20. Vickie Shuffitt, PT, Scott Hoskinson, MD and Carol Matsumoto, RN, CWOCN Wound Care Program, Maui Memorial Medical Center, Wailuku, HI “Silver Antimicrobial Hydrogel Eradicates Bioburden and Hastens Discharge for Acute Care Facility”
  21. Gibbins, Bruce PhD and Karandikar, Bhalchandra PhD AcryMed, Inc., Portland, OR July 2005 “Novel Silver Antimicrobial Treatment”
  22. Susan Girolami, BSN, RN, CWOCN Therapy Support, Inc., Cincinnati, OH April 2006 “Combining Ionic Silver Wound Hydrogel and Negative Pressure for Limb Salvage”
  23. Cameron Field, DPM and Kenneth Morgan, DPM HealthOne Alliance Presbyterian/St. Lukes, Denver, CO April 2006 “External Fixation Pin Care Protocol Utilizing Ionic Silver Site Dressings”
  24. Mary Webb, RN, BSN, MA, CIC San Mateo Medical Center, San Mateo, CA April 2006 “Use of Ionic Silver and Collagen to Reduce Bioburden and Promote Healing for Improved Quality of Life in a Complex Patient”



Briana McDonald-natural health writer and contributor to the Silver Bulletin e-News Magazine (Utopia Silver Supplements). She does free-lance health article writing as well as website and ad design.

(© Common Law Copyright claimed by the owners and principles of and Skonestein, Int’l. This article may be republished without written permission, but with all credits and links.)



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