Most People are Deficient of Vitamin B12 and Their Symptoms Are Misdiagnosed

March 11, 2015

by Paul Fassa, Natural Health Journalist

( Vitamin B12 is a vitamin that gets little or no mention in most health publications, and too many health practitioners are unaware of its importance and know what to look for. The truth is most people are deficient of Vitamin B12 and their symptoms are misdiagnosed.

As a matter of fact, it may be the first thing to assess or even try because adding vitamin B12 with the right type of that vitamin could be the first thing to consider for several symptoms, including chronic fatigue, neurological disorders, and even MS-like symptoms and other disorders that are vague or misleading.

If vitamin B12 deficiency is not the first thing checked properly, it could lead to the wrong and dangerous pharmaceutical interventions. There are no dangerous side effects from too much vitamin B12, as long as the rest of one’s vitamin B complex is sufficient as a foundation.

All the usual B12 sources, such as meat, eggs, and dairy won’t do much if one’s small intestines are lacking the intrinsic factor. The intrinsic factor is a special protein produced in the small intestine that is key to extracting B12 from foods and assimilating it into the blood.

And many lack it due to our standard American diet (SAD) of processed foods and/or anti-acid medications, prescribed or over the counter. Actually, it’s usually a lack of stomach acid that’s the problem, not excess acid. So anti-acids make those apparent excess acid situations even worse.

That’s why meat and dairy consumers are not exempt from vitamin B12 deficiency. The usual symptoms of fatigue, depression, anxiety, and anemia and many more physical and neurological manifestations are diagnosed without first checking vitamin B12 levels correctly. Regardless of diet, it’s estimated up to 80 percent of the population may be vitamin B12 deficient.

A Large California Study, Stomach Acid, and the Proper Type of Vitamin B12

In a recent study, researchers compared the medical records of nearly 26,000 members the Northern California Kaiser Permanente sick, er health care provider plan who were diagnosed with a vitamin B12 deficiency between 1997 and 2011, and nearly 185,000 people with healthy B12 levels. The study determined an association of using acid reducing prescribed and over the counter pharmaceuticals to vitamin B-12 deficiency.

According to holistic Dr. Jonathon Wright of the Tacoma Clinic, it takes sufficient stomach acid to begin extracting vitamin B12 from food. Most have too little acid, not too much. That and a well balanced gut microbiota are necessary. They tend to deteriorate as we age, especially while indulging in our SAD (standard American diet) and high antibiotic use. This usually results in bouts of fatigue and leads to increased cardiovascular risk.

But supplementing works fine if one uses the right type of B12 taken sublingually or transdermally via patches or lipid encapsulated (liposomal) or by injection. There are three types of B12: cyanocobalamin, hydroxycabalamin, and methylcobalamin. Of these three, most experts agree that methylcobalamin is the most effective.

How to Check for Optimum Vitamin B-12 Levels

Vitamin B-12 deficiency is often behind low energy, chronic fatigue, anemia, and allows too much homocysteine build-up, a reliable marker for impending cardiac arrest. Blood serum testing has a problem because it doesn’t take into consideration what’s called the intrinsic value, the potential for metabolizing B12 on a cellular level.

Testing urine for high amounts of Methylmalonic Acid (MMA) is more accurate than blood level testing. MMA is high when B-12 metabolism is low. Another indirect indicator is a high homocysteine blood level. High homocysteine levels lead to cardiac problems. As indirect indicators, both MMA and homocysteine have inverse relationships to B12 levels.

However the most commonly injected B-12 by AMA doctors is cyanocobalamin, which many say actually impedes B-12 metabolism. Methylocobalamin B12 helps change homocysteine into methionine. Less homocysteine is a good thing for those flirting with cardiovascular issues.

So regardless of whatever method you use to supplement B12: sublingual lozenges, transdermal patches, liposomal formulas, or injections, use only methylocobalamin. And make sure your B6 and folate levels are adequate to optimize the B12 intake. Don’t use potentially toxic synthetic folic acid as a source of folate. Make sure your source of B vitamins says folate, not folic acid.

If MMA and homocysteine blood testing is not available or beyond budget, there is little concern for overdosing. Some estimate that oral sublingual ingestion of 1000 mcg (micograms) of B12 daily for at least a month or more approximates twice weekly B12 injections. But I think that is not true for everyone.

I take three times that much sublingually daily. The idea is to take whatever supplement method of B12 bypasses the gut and gets into your bloodstream as directly as possible, and not to worry about overdosing.

While living in Mexico, I injected myself two to three times a week for awhile to help me cope with a difficult period of my wife’s illness. In Mexico you can purchase disposable syringes with needles for less than a quarter each. And I had an over the counter pharmacy source for methylocobalamin at around a dollar per vial. Each injection required one vial. So where’s the medical freedom in the USA? It doesn’t exist.

Interesting BBC Report on the UK Doctor Who Disagrees with the Chosen Levels of B12

For more on how much B12 is not too much, discover the UK doctor in this video who cured misdiagnosed MS and chronic fatigue patients by injecting them with B12 even while their B12 blood levels were considered already well above normal. A couple of his more serious patients who were previously misdiagnosed but now successfully treated with Dr. Chandy’s heavy handed B12 approach were interviewed.

For that, the British Health System ordered him to drop dealing with his patients that way until double-blind placebo testing could verify his results.

Dr. Joseph Chandy has treated hundreds of patients successfully with high dose B12 injections. He refused to back down, saying that his case records provide all the proof needed, and subjecting B12 deficient patients to placebos required by the double blind testing procedures was inhumane.

When you know something works without adverse side effects, why deprive people of it just to satisfy a bureaucratic demand? Good show Dr. Chandy, well done! In case you missed the embedded hyperlink, here’s that short BBC video report on Dr. Chandy and his patients –

Sources for More Information:

Dr. Jonathon Wright interview on B12 –